Principles
19 of 529 shown
Claim Board — scientifically-declared inventory awaiting external contributors. Each stub is an open invitation: author the reference solver + dataset, open a PR, and earn the registration bounty. Not mineable until promoted to Tier 1/2 by 3-of-5 multisig.
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Problem classnonlinear_inverse (203)linear_inverse (197)parameter_estimation (62)linear_inverse_with_categorical_readout (18)statistical_inverse (5)forward (3)parametric_spectral_estimation (3)linear_inverse_count (3)
Noise modelgaussian (316)shot_poisson (80)poisson (28)observation_gaussian (13)poisson_gaussian (13)measurement_gaussian (10)lognormal (9)deterministic (7)
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| Title | ID | Chain | Domain | Tier | δ | L_DAG | Specs | Benchmarks |
|---|---|---|---|---|---|---|---|---|
| Hodgkin-Huxley Neuron Model Parameter Estimation | L1-396 | unregistered | Computational Biology | 📋 Stub — not mineable | 5 | 3.5 | 0 | 0 |
| FitzHugh-Nagumo Excitability Model | L1-397 | unregistered | Computational Biology | 📋 Stub — not mineable | 3 | 2.5 | 0 | 0 |
| Cable Equation (Dendrite Propagation) | L1-398 | unregistered | Computational Biology | 📋 Stub — not mineable | 3 | 3 | 0 | 0 |
| Cardiac Electrophysiology (Monodomain) | L1-399 | unregistered | Computational Biology | 📋 Stub — not mineable | 5 | 4.5 | 0 | 0 |
| Hemodynamics (Navier-Stokes Cardiovascular) | L1-400 | unregistered | Computational Biology | 📋 Stub — not mineable | 5 | 4.5 | 0 | 0 |
| Windkessel Cardiac Afterload Model | L1-401 | unregistered | Computational Biology | 📋 Stub — not mineable | 3 | 2.2 | 0 | 0 |
| Pharmacokinetics Compartment Model | L1-402 | unregistered | Computational Biology | 📋 Stub — not mineable | 3 | 2.5 | 0 | 0 |
| Physiologically Based PK (PBPK) | L1-403 | unregistered | Computational Biology | 📋 Stub — not mineable | 5 | 4 | 0 | 0 |
| Pharmacodynamics Dose-Response Inversion | L1-404 | unregistered | Computational Biology | 📋 Stub — not mineable | 3 | 2 | 0 | 0 |
| SIR Epidemic Parameter Estimation | L1-405 | unregistered | Computational Biology | 📋 Stub — not mineable | 3 | 2.5 | 0 | 0 |
| SEIR Epidemic with Exposed Compartment | L1-406 | unregistered | Computational Biology | 📋 Stub — not mineable | 3 | 2.8 | 0 | 0 |
| Lotka-Volterra Predator-Prey Dynamics | L1-407 | unregistered | Computational Biology | 📋 Stub — not mineable | 3 | 2.5 | 0 | 0 |
| Wright-Fisher Population Genetics | L1-408 | unregistered | Computational Biology | 📋 Stub — not mineable | 5 | 3 | 0 | 0 |
| Phylogenetic Likelihood Inference | L1-409 | unregistered | Computational Biology | 📋 Stub — not mineable | 5 | 4.5 | 0 | 0 |
| Tumor Growth Model Inversion | L1-410 | unregistered | Computational Biology | 📋 Stub — not mineable | 3 | 2.5 | 0 | 0 |
| Oxygen Transport (Krogh Cylinder) | L1-411 | unregistered | Computational Biology | 📋 Stub — not mineable | 3 | 2.8 | 0 | 0 |
| Protein Folding Energy Landscape Inversion | L1-412 | unregistered | Computational Biology | 📋 Stub — not mineable | 50 | 6.5 | 0 | 0 |
| HMM Sequence Alignment and Profile Inference | L1-413 | unregistered | Computational Biology | 📋 Stub — not mineable | 5 | 3.5 | 0 | 0 |
| RNA-seq Cell-Type Classification (PWDR) | L1-520 | unregistered | Computational Biology | 📋 Stub — not mineable | 5 | 8.3 | 0 | 0 |