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Cardiac Electrophysiology (Monodomain) L1-399

Computational BiologyCardiac modelingδ=5 · challengingL_DAG = 4.5📋 Stub — not mineable
📋

Unclaimed Principle — open for contribution

This Principle is declared in the catalog but has no reference solver, no pinned dataset, and is not registered on-chain. There is no reward pool. Submitting a cert against this Principle today will record the cert for reproducibility but pay zero PWM.

To claim it as a Bounty #7 contribution: open a PR adding (1) a reference solver, (2) ≥1 dataset pinned to IPFS, (3) updates to the L3 manifest with dataset CIDs. After verifier-agent triple-review, the founders' 3-of-5 multisig signs PWMRegistry.register() and the Principle becomes mineable.

Forward model E

Cardiac Electrophysiology (Monodomain): Cardiac EP inversion: recover 3D transmembrane potential distribution from body surface ECG recordings. The forward operator produces the measurement through a 3-node primitive DAG (M.pde.monodomain_bidomain…); recovery is posed as a nonlinear_inverse problem. Difficulty tier delta=5 with effective condition number kappa_eff~2000; torso_conductivity_uncertainty, electrode_placement_error_mm set the accuracy floor at the Omega boundary. See the forward_model field for the closed-form equation.

L-DAG

D.space -> S.eikonal.fast_marching -> O.ecg.inverse_body_surface
D.spaceS.eikonal.fast_marchingO.ecg.inverse_body_surface

Well-posedness W

Existence:
true
Uniqueness:
true
Stability:
conditional
κ:
100000

Existence of the recovered 3D_transmembrane_potential is guaranteed within the declared Omega bounds. Uniqueness holds on the measurement-supported subspace; out-of-support modes are controlled by declared priors. Stability is conditionally stable (kappa_eff ~= 2000); torso_conductivity_uncertainty dominates the stability cliff; the remaining mismatch parameters contribute higher-order bias terms. Observation gaussian sets the irreducible data-fidelity floor.

Solvability C

Solver class:
statistical [Tikhonov_regularization or Bayesian_electrocardiographic_imaging]
Convergence rate q:
2
Complexity:
O(N_mesh_nodes ** 2) for transfer matrix computation per iteration

Specs (0)

No L2 specs registered yet for this principle.