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Oxygen Transport (Krogh Cylinder) L1-411

Computational BiologyPhysiologyδ=3 · standardL_DAG = 2.8📋 Stub — not mineable
📋

Unclaimed Principle — open for contribution

This Principle is declared in the catalog but has no reference solver, no pinned dataset, and is not registered on-chain. There is no reward pool. Submitting a cert against this Principle today will record the cert for reproducibility but pay zero PWM.

To claim it as a Bounty #7 contribution: open a PR adding (1) a reference solver, (2) ≥1 dataset pinned to IPFS, (3) updates to the L3 manifest with dataset CIDs. After verifier-agent triple-review, the founders' 3-of-5 multisig signs PWMRegistry.register() and the Principle becomes mineable.

Forward model E

Oxygen Transport (Krogh Cylinder): Krogh cylinder model inversion: estimate oxygen diffusivity D and consumption rate Q from tissue pO2 measurements. The forward operator produces the measurement through a 3-node primitive DAG (M.pde.krogh_cylinder…); recovery is posed as a parameter_estimation problem. Difficulty tier delta=3 with effective condition number kappa_eff~50; non_uniform_capillary_spacing, convection_neglect set the accuracy floor at the Omega boundary. See the forward_model field for the closed-form equation.

L-DAG

D.space -> S.fdm.oxygen_diffusion -> O.chi2.po2_profile
D.spaceS.fdm.oxygen_diffusionO.chi2.po2_profile

Well-posedness W

Existence:
true
Uniqueness:
true
Stability:
conditional
κ:
1000

Existence of the recovered oxygen_distribution_field is guaranteed within the declared Omega bounds. Uniqueness holds on the measurement-supported subspace; out-of-support modes are controlled by declared priors. Stability is conditionally stable (kappa_eff ~= 50); non_uniform_capillary_spacing dominates the stability cliff; the remaining mismatch parameters contribute higher-order bias terms. Gaussian sets the irreducible data-fidelity floor.

Solvability C

Solver class:
classical [FDM_Krogh_cylinder or analytical_Krogh_solution]
Convergence rate q:
2
Complexity:
O(N_radial_nodes) per steady-state solve per iteration

Specs (0)

No L2 specs registered yet for this principle.