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Confocal Z-Stack (3D axial deconvolution) L1-533

Microscopy3D confocal volume imagingδ=3 · standardL_DAG = 3📋 Stub — not mineable
📋

Unclaimed Principle — open for contribution

This Principle is declared in the catalog but has no reference solver, no pinned dataset, and is not registered on-chain. There is no reward pool. Submitting a cert against this Principle today will record the cert for reproducibility but pay zero PWM.

To claim it as a Bounty #7 contribution: open a PR adding (1) a reference solver, (2) ≥1 dataset pinned to IPFS, (3) updates to the L3 manifest with dataset CIDs. After verifier-agent triple-review, the founders' 3-of-5 multisig signs PWMRegistry.register() and the Principle becomes mineable.

Forward model E

Confocal Z-Stack (3D axial deconvolution): confocal laser scan produces the measurement through a 4-node primitive DAG K.psf.confocal -> S.scan.raster -> S.scan.axial -> int.temporal, with axial/z-step integration and Poisson signal noise + Gaussian read noise. Recovery is posed as a linear inverse problem that inverts the forward operator to estimate the scene-side 3D intensity. Difficulty tier delta=3 with effective condition number kappa_eff~12; calibration-level mismatch (z_step_error, pinhole_size_AU, spherical_aberration) sets the accuracy floor at the Omega boundary. See the forward_model field for the closed-form imaging equation.

L-DAG

K.psf.confocal -> S.scan.raster -> S.scan.axial -> int.temporal
K.psf.confocalS.scan.rasterS.scan.axialint.temporal

Well-posedness W

Existence:
true
Uniqueness:
true
Stability:
conditional
κ:
240

Existence of the recovered 3D intensity is guaranteed within the declared Omega bounds. Uniqueness holds on the measurement-supported subspace; out-of-support modes are controlled by the declared priors. Stability is moderately conditioned (kappa_eff ~= 12); z_step_error dominates the stability cliff; pinhole_size_AU and the remaining mismatch parameters contribute higher-order bias terms. Poisson signal noise + gaussian read noise sets the irreducible data-fidelity floor, while mild Tikhonov or analytic inversion is sufficient at the nominal Omega point.

Solvability C

Solver class:
iterative maximum-likelihood (Richardson-Lucy class) [Richardson-Lucy-3D] | linear-operator + convex optimisation [DeconvolutionLab2] | linear-operator + deep neural prior [Content-Aware-3D]
Convergence rate q:
2
Complexity:
O(H * W * Z * log(...)) per iteration; learned variants: O(H W Z * F_theta_cost) per forward pass

Specs (0)

No L2 specs registered yet for this principle.