Contrast-Enhanced Ultrasound (CEUS) L1-062
Unclaimed Principle — open for contribution
This Principle is declared in the catalog but has no reference solver, no pinned dataset, and is not registered on-chain. There is no reward pool. Submitting a cert against this Principle today will record the cert for reproducibility but pay zero PWM.
To claim it as a Bounty #7 contribution: open a PR adding (1) a reference solver, (2) ≥1 dataset pinned to IPFS, (3) updates to the L3 manifest with dataset CIDs. After verifier-agent triple-review, the founders' 3-of-5 multisig signs PWMRegistry.register() and the Principle becomes mineable.
Forward model E
Contrast-Enhanced Ultrasound (CEUS): contrast enhanced ultrasound produces the measurement through a 4-node primitive DAG L.emit.acoustic_pulse -> L.microbubble_oscillate -> L.harmonic_separate -> int.temporal, with time-integrated exposure and additive Gaussian thermal/electronic noise. Recovery is posed as a non-convex inverse problem that inverts the forward operator to estimate the scene-side 2D perfusion map. Difficulty tier delta=3 with effective condition number kappa_eff~11; calibration-level mismatch (bubble_destruction, nonlinear_tissue_harmonics, flow_artifacts) sets the accuracy floor at the Omega boundary. See the forward_model field for the closed-form imaging equation.
L-DAG
Well-posedness W
- Existence:
- true
- Uniqueness:
- true
- Stability:
- conditional
- κ:
- 220
Existence of the recovered 2D perfusion map is guaranteed within the declared Omega bounds. Uniqueness is local rather than global (non-convex landscape); convergence depends on initialisation and priors. Stability is moderately conditioned (kappa_eff ~= 11); bubble_destruction dominates the stability cliff; nonlinear_tissue_harmonics and the remaining mismatch parameters contribute higher-order bias terms. Additive gaussian thermal/electronic noise sets the irreducible data-fidelity floor, while mild Tikhonov or analytic inversion is sufficient at the nominal Omega point.
Solvability C
- Solver class:
- linear-operator + convex optimisation [Pulse-Inversion, Amplitude-Mod] | linear-operator + deep neural prior [CEUS-Net]
- Convergence rate q:
- 2
- Complexity:
- O(H * W * log(...)) per iteration; learned variants: O(H W Z * F_theta_cost) per forward pass