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Proton Therapy (proton-beam radiation dose imaging) L1-051

Medical ImagingDose-deposition imaging for Bragg-peak therapyδ=5 · challengingL_DAG = 4📋 Stub — not mineable
📋

Unclaimed Principle — open for contribution

This Principle is declared in the catalog but has no reference solver, no pinned dataset, and is not registered on-chain. There is no reward pool. Submitting a cert against this Principle today will record the cert for reproducibility but pay zero PWM.

To claim it as a Bounty #7 contribution: open a PR adding (1) a reference solver, (2) ≥1 dataset pinned to IPFS, (3) updates to the L3 manifest with dataset CIDs. After verifier-agent triple-review, the founders' 3-of-5 multisig signs PWMRegistry.register() and the Principle becomes mineable.

Forward model E

Proton Therapy (proton-beam radiation dose imaging): proton therapy dose produces the measurement through a 4-node primitive DAG L.proton_accelerator -> L.bragg_peak_energy_deposition -> D.dose_meter -> int.spatial, with spatially-projected accumulation and photon-shot-noise-limited (Poisson counting). Recovery is posed as a non-convex inverse problem that inverts the forward operator to estimate the scene-side 3D dose distribution. Difficulty tier delta=5 with effective condition number kappa_eff~15; calibration-level mismatch (range_uncertainty, organ_motion, tissue_heterogeneity) sets the accuracy floor at the Omega boundary. See the forward_model field for the closed-form imaging equation.

L-DAG

L.proton_accelerator -> L.bragg_peak_energy_deposition -> D.dose_meter -> int.spatial
L.proton_acceleratorL.bragg_peak_energy_depositionD.dose_meterint.spatial

Well-posedness W

Existence:
true
Uniqueness:
true
Stability:
conditional
κ:
300

Existence of the recovered 3D dose distribution is guaranteed within the declared Omega bounds. Uniqueness is local rather than global (non-convex landscape); convergence depends on initialisation and priors. Stability is moderately conditioned (kappa_eff ~= 15); range_uncertainty dominates the stability cliff; organ_motion and the remaining mismatch parameters contribute higher-order bias terms. Photon-shot-noise-limited (poisson counting) sets the irreducible data-fidelity floor, while mild Tikhonov or analytic inversion is sufficient at the nominal Omega point.

Solvability C

Solver class:
linear-operator + convex optimisation [Analytical-Dose] | iterative projection (ADMM / GAP) + optimisation [Monte-Carlo] | linear-operator + deep neural prior [Proton-Net]
Convergence rate q:
2
Complexity:
O(H * W * Z * log(...)) per iteration; learned variants: O(H W Z * F_theta_cost) per forward pass

Specs (0)

No L2 specs registered yet for this principle.