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Zernike Phase-Contrast Microscopy L1-017

MicroscopyLabel-free phase visualizationδ=3 · standardL_DAG = 3📋 Stub — not mineable
📋

Unclaimed Principle — open for contribution

This Principle is declared in the catalog but has no reference solver, no pinned dataset, and is not registered on-chain. There is no reward pool. Submitting a cert against this Principle today will record the cert for reproducibility but pay zero PWM.

To claim it as a Bounty #7 contribution: open a PR adding (1) a reference solver, (2) ≥1 dataset pinned to IPFS, (3) updates to the L3 manifest with dataset CIDs. After verifier-agent triple-review, the founders' 3-of-5 multisig signs PWMRegistry.register() and the Principle becomes mineable.

Forward model E

Zernike Phase-Contrast Microscopy: phase plate interference produces the measurement through a 3-node primitive DAG L.phase_plate -> L.modulus_squared -> int.temporal, with time-integrated exposure and additive Gaussian thermal/electronic noise. Recovery is posed as a non-convex inverse problem that inverts the forward operator to estimate the scene-side 2D phase. Difficulty tier delta=3 with effective condition number kappa_eff~10; calibration-level mismatch (phase_plate_alignment, halo_artifact, annulus_diaphragm_drift) sets the accuracy floor at the Omega boundary. See the forward_model field for the closed-form imaging equation.

L-DAG

L.phase_plate -> L.modulus_squared -> int.temporal
L.phase_plateL.modulus_squaredint.temporal

Well-posedness W

Existence:
true
Uniqueness:
true
Stability:
conditional
κ:
200

Existence of the recovered 2D phase is guaranteed within the declared Omega bounds. Uniqueness is local rather than global (non-convex landscape); convergence depends on initialisation and priors. Stability is moderately conditioned (kappa_eff ~= 10); phase_plate_alignment dominates the stability cliff; halo_artifact and the remaining mismatch parameters contribute higher-order bias terms. Additive gaussian thermal/electronic noise sets the irreducible data-fidelity floor, while mild Tikhonov or analytic inversion is sufficient at the nominal Omega point.

Solvability C

Solver class:
linear-operator + convex optimisation [TIE-Phase] | linear-operator + deep neural prior [PhaseCNN] | iterative projection (ADMM / GAP) + optimisation [Gerchberg-Saxton]
Convergence rate q:
2
Complexity:
O(H * W * log(...)) per iteration; learned variants: O(H W Z * F_theta_cost) per forward pass

Specs (0)

No L2 specs registered yet for this principle.