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Stimulated Emission Depletion (STED) — donut super-resolution L1-010

MicroscopyDonut-PSF super-resolution microscopyδ=5 · challengingL_DAG = 3.8📋 Stub — not mineable
📋

Unclaimed Principle — open for contribution

This Principle is declared in the catalog but has no reference solver, no pinned dataset, and is not registered on-chain. There is no reward pool. Submitting a cert against this Principle today will record the cert for reproducibility but pay zero PWM.

To claim it as a Bounty #7 contribution: open a PR adding (1) a reference solver, (2) ≥1 dataset pinned to IPFS, (3) updates to the L3 manifest with dataset CIDs. After verifier-agent triple-review, the founders' 3-of-5 multisig signs PWMRegistry.register() and the Principle becomes mineable.

Forward model E

y(r) = [PSF_sted(r; P_depl) conv f(r)] + n; effective FWHM = FWHM_0 / \sqrt{1 + P_depl/P_sat)

Stimulated Emission Depletion (STED) — donut super-resolution: sted donut depletion produces the measurement through a 3-node primitive DAG L.excitation.focused -> L.depletion.donut -> int.temporal, with time-integrated exposure and photon-shot-noise-limited (Poisson counting). Recovery is posed as a linear inverse problem that inverts the forward operator to estimate the scene-side 2D intensity. Difficulty tier delta=5 with effective condition number kappa_eff~20; calibration-level mismatch (donut_zero_depth, depletion_power_drift, anti_stokes_leakage) sets the accuracy floor at the Omega boundary. See the forward_model field for the closed-form imaging equation.

L-DAG

L.excitation.focused -> L.depletion.donut -> int.temporal
L.excitation.focusedL.depletion.donutint.temporal

Well-posedness W

Existence:
true
Uniqueness:
true
Stability:
conditional
κ:
400

Existence of the recovered 2D intensity is guaranteed within the declared Omega bounds. Uniqueness holds on the measurement-supported subspace; out-of-support modes are controlled by the declared priors. Stability is moderately conditioned (kappa_eff ~= 20); donut_zero_depth dominates the stability cliff; depletion_power_drift and the remaining mismatch parameters contribute higher-order bias terms. Photon-shot-noise-limited (poisson counting) sets the irreducible data-fidelity floor, while TV / wavelet-sparsity / deep priors stabilise recovery at the ill-conditioned end of Omega.

Solvability C

Solver class:
iterative maximum-likelihood (Richardson-Lucy class) [Richardson-Lucy-STED] | linear-operator + convex optimisation [TV-ADMM-STED] | linear-operator + deep neural prior [STED-Net]
Convergence rate q:
2
Complexity:
O(H * W * log(...)) per iteration; learned variants: O(H W Z * F_theta_cost) per forward pass

Specs (0)

No L2 specs registered yet for this principle.